裴钢
科学的看法】
裴钢院士:如果你喜欢科学,就要脚踏实地
“动机”(Motivation),中国科学院上海生命科学研究院院长裴钢院士用这个词作为对研究生们的第一个建议,“你首先要有非常强烈的动机和动力,如果你喜欢科学,我建议你就努力去做,如果不喜欢,那就趁早挑选你喜欢的事去做。”在裴钢看来,研究生应具有的第二个素质是“矢志不移”(persistency),“你要永远不停地努力。一定要脚踏实地,基本功都要掌握好。”
“团队合作精神”和“创新”,是裴钢院士对研究生的另外两个希望,他说:“科学研究是一项社会性活动,要和其他人合作来做。做科学本身就是追求真善美,没有必要的胸襟,不会与别人合作,就什么事情也做不好。”“科学和艺术一样,永远要创新,总要做和别人不一样的东西 (to be different)。”
2006年3月24日,在参加中科院研究生院学位评定委员会第二届第6次会议期间,裴钢院士接受了“研究生教育访谈录”的专题采访。访谈中,裴钢院士谈到了对国立研究机构科研与研究生教育协调发展的观点、上海生科院研究生教育的具体做法,以及他本人从事科研和教育工作的体会、对研究生们的期望与建议。
Shi Y, Feng Y, Kang J, Liu C, Li Z, Li D, Cao W, Qiu J, Guo Z, Bi E, Zang L,Lu C, Zhang JZ, Pei G. Critical regulation of CD4+ T cell survival and autoimmUnity by β-arrestin 1. Nat Immunol. 2007;8(8):817-24.
Zou L, Yang R, Chai J, Pei G. Rapid xenograft tumor prOGREssion in beta-arrestin1 transgenic mice due toenhanced tumor angiogenesis. FASEB J. 2008 ;22(2):355-64.
Ma L, Pei G. Beta-arrestin signaling and regulation of transcription. J Cell Sci. 2007;120(2):213-8.
Ni Y, Zhao X, Bao G, Zou L, Teng L, Wang Z, Song M, Pei G. Activation of b2-adrenergic receptor stimulates g-secretase activity and accelerates amyloid plaque formation. Nat Med. 2006;12(12):1390-6.
Yu Y, Shen L, Xia P, Tang Y, Pei G. Syntaxin 1A Promotes the Endocytic Sorting of EAAC1 Leading to Inhibition of Glutamate Transport. J Cell Sci. 2006;119(18):3776-87.
Fan H, Fan F, Bao L, Pei G. SNAP-25/syntaxin 1A complex functionally modulates neurotranSMItter GABA reuptake. J Biol Chem. 2006;281(38):28174-84.
Wang Y, Tang Y, Teng L, Wu Y, Zhao X, Pei G. β-Arrestins negatively regulate Toll-like/interleukin 1-receptor signaling through their functional interaction with TRAF6. Nat Immunol. 2006;7(2):139-47.
Luan B, Zhang Z, Wu Y, Kang J, Pei G. β-Arrestin2 Functions as a Phosphorylation Regulated Suppressor to UV-Induced NF-kB Activation. EMBO J. 2005;24(24):4237-46.
Kang J, Shi Y, Xiang B, Qu B, Su W, Zhu M, Zhang M, Bao G, Pei G, Ma L. Novel nuclear function of β-arrestin 1: regulation of histone acetylation and gene transcription. Cell. 2005;123(5):833-47.
Guan JS, Xu ZZ, Gao H, He SQ, Ma GQ, Sun T, Wang LH, Zhang ZN, Lena I,Kitchen I, Elde R, Zimmer A, He C, Pei G, Bao L, and Zhang X. Interaction with Vesicle Luminal Protachykinin Regulates Surface Expression of δ-Opioid Receptors and Opioid Analgesia. Cell. 2005;122(4):619-631.
Xu NJ, Yu YX, Zhu JM, Liu H, Shen L, Zeng R, Zhang X, Pei G. Inhibition of SNAP-25 phosphorylation at Ser187 is involved in chronic morphine-induced down-regulation of SNARE complex formation. J Biol Chem. 2004;279(39):40601-8.
Gao H, Sun Y, Wu Y, Luan B, Wang Y, Qu B, Pei G. Identification of beta-Arrestin2 as a G Protein-Coupled Receptor-Stimulated Regulato
裴钢院士:如果你喜欢科学,就要脚踏实地
“动机”(Motivation),中国科学院上海生命科学研究院院长裴钢院士用这个词作为对研究生们的第一个建议,“你首先要有非常强烈的动机和动力,如果你喜欢科学,我建议你就努力去做,如果不喜欢,那就趁早挑选你喜欢的事去做。”在裴钢看来,研究生应具有的第二个素质是“矢志不移”(persistency),“你要永远不停地努力。一定要脚踏实地,基本功都要掌握好。”
“团队合作精神”和“创新”,是裴钢院士对研究生的另外两个希望,他说:“科学研究是一项社会性活动,要和其他人合作来做。做科学本身就是追求真善美,没有必要的胸襟,不会与别人合作,就什么事情也做不好。”“科学和艺术一样,永远要创新,总要做和别人不一样的东西 (to be different)。”
2006年3月24日,在参加中科院研究生院学位评定委员会第二届第6次会议期间,裴钢院士接受了“研究生教育访谈录”的专题采访。访谈中,裴钢院士谈到了对国立研究机构科研与研究生教育协调发展的观点、上海生科院研究生教育的具体做法,以及他本人从事科研和教育工作的体会、对研究生们的期望与建议。
【发表论文】
Shi Y, Feng Y, Kang J, Liu C, Li Z, Li D, Cao W, Qiu J, Guo Z, Bi E, Zang L,Lu C, Zhang JZ, Pei G. Critical regulation of CD4+ T cell survival and autoimmUnity by β-arrestin 1. Nat Immunol. 2007;8(8):817-24.
Zou L, Yang R, Chai J, Pei G. Rapid xenograft tumor prOGREssion in beta-arrestin1 transgenic mice due toenhanced tumor angiogenesis. FASEB J. 2008 ;22(2):355-64.
Ma L, Pei G. Beta-arrestin signaling and regulation of transcription. J Cell Sci. 2007;120(2):213-8.
Ni Y, Zhao X, Bao G, Zou L, Teng L, Wang Z, Song M, Pei G. Activation of b2-adrenergic receptor stimulates g-secretase activity and accelerates amyloid plaque formation. Nat Med. 2006;12(12):1390-6.
Yu Y, Shen L, Xia P, Tang Y, Pei G. Syntaxin 1A Promotes the Endocytic Sorting of EAAC1 Leading to Inhibition of Glutamate Transport. J Cell Sci. 2006;119(18):3776-87.
Fan H, Fan F, Bao L, Pei G. SNAP-25/syntaxin 1A complex functionally modulates neurotranSMItter GABA reuptake. J Biol Chem. 2006;281(38):28174-84.
Wang Y, Tang Y, Teng L, Wu Y, Zhao X, Pei G. β-Arrestins negatively regulate Toll-like/interleukin 1-receptor signaling through their functional interaction with TRAF6. Nat Immunol. 2006;7(2):139-47.
Luan B, Zhang Z, Wu Y, Kang J, Pei G. β-Arrestin2 Functions as a Phosphorylation Regulated Suppressor to UV-Induced NF-kB Activation. EMBO J. 2005;24(24):4237-46.
Kang J, Shi Y, Xiang B, Qu B, Su W, Zhu M, Zhang M, Bao G, Pei G, Ma L. Novel nuclear function of β-arrestin 1: regulation of histone acetylation and gene transcription. Cell. 2005;123(5):833-47.
Guan JS, Xu ZZ, Gao H, He SQ, Ma GQ, Sun T, Wang LH, Zhang ZN, Lena I,Kitchen I, Elde R, Zimmer A, He C, Pei G, Bao L, and Zhang X. Interaction with Vesicle Luminal Protachykinin Regulates Surface Expression of δ-Opioid Receptors and Opioid Analgesia. Cell. 2005;122(4):619-631.
Xu NJ, Yu YX, Zhu JM, Liu H, Shen L, Zeng R, Zhang X, Pei G. Inhibition of SNAP-25 phosphorylation at Ser187 is involved in chronic morphine-induced down-regulation of SNARE complex formation. J Biol Chem. 2004;279(39):40601-8.
Gao H, Sun Y, Wu Y, Luan B, Wang Y, Qu B, Pei G. Identification of beta-Arrestin2 as a G Protein-Coupled Receptor-Stimulated Regulato